Postdoctoral fellow/Research Associate

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Postdoctoral fellow/Research Associate
7 {) U0 s/ y( K9 HOttawa Hospital Research Institute
Ottawa, Ontario, Canada

' @+ t, J7 s! b; XJob Duration: 1-2 Years
- z9 P9 x6 g! p; {& xRequired Travel: None
( K% H, ]/ V% z6 d3 t( w$ M$ d, APosition Title: Postdoctoral fellow/Research Associate
Industry: Cell Biology
Min Education: Ph.D.
Posted: January 4, 2010
$ F0 ?! E: \6 D9 E) tMin Experience: 0-1 Year
Job Function: Postdoctoral Training
/ E1 w: y! z' \Job Type: Full-Time
. e1 D1 s4 t& N* y1 X3 ISalary: Yearly Salary)

$ v& e) T0 b( ?0 L3 q3 ^CIHR/NSERC-funded postdoctoral fellow/research associate positions are available in the laboratory of Dr. Nongnuj Tanphaichitr to study molecular mechanisms of how (sulfo)glycolipids including: 1) sulfogalactosylglycerolipid (SGG, also known as seminolipid), 2) sulfogalactosylceramide (SGC, also known as sulfatide), and 3) galactosylceramide (GC) participate in cell-cell/extracellular matrix interactions. We are interested in two interaction processes.  The first involves sperm SGG in the binding to the egg extracellular matrix (the zona pellucida-ZP), and in capturing epididymal fluid proteins such as arylsulfatase A (another ZP binding protein, as part of sperm maturation) and antimicrobial peptides (as provision of innate immunity to the gametes).  In the second process, we want to investigate the roles of SGG, SGC and GC, present on the vaginal epithelial cell surface, in HIV-1 passage through the vaginal mucosa. The successful candidate will use cutting-edge lipidomics and proteomics analyses, cell biology and imaging, molecular biology, immunology and animal biology approaches in the studies.


( Q# W( _6 G! P9 v, n7 v- vJob Requirements
$ U: V4 x$ Q) ]) {( H
The postdoctoral candidate must have a Ph.D. degree in basic science with a broad background in biological sciences, critical thinking ability in experimental design and interpretation and good written and oral communication skills.  Experience in glycolipid/lipid and/or immunology work is considered a great asset.

Contact Person: Dr. Nongnuj Tanphaichitr
Email Address: ntanphaichitr@ohri.ca

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